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Similar content being viewed by others Introduction Proteostasis, or protein homeostasis, refers to the intricate balance of processes that regulate protein synthesis, folding, trafficking, and degradation to sustain a functional proteome throughout life

While epigenetic clocks are widely utilized to quantify biological aging, these tools remain inadequately standardized, resulting in poor reproducibility and limited cross-study comparability across laboratories

However, these comparisons are speculative and have not been validated in robust human clinical trials

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